Wen-Cai Ye Selected Research

chan su (ChanSu)

2/2021	1β-OH-arenobufagin induces mitochondrial apoptosis in hepatocellular carcinoma through the suppression of mTOR signaling pathway.
4/2019	Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolides from toad venom.
1/2017	Fibroblast Activation Protein α Activated Tripeptide Bufadienolide Antitumor Prodrug with Reduced Cardiotoxicity.
8/2014	Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt.
10/2012	Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis.

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Wen-Cai Ye Research Topics

Disease

33	Neoplasms (Cancer) 02/2021 - 11/2002
9	Hepatocellular Carcinoma (Hepatoma) 02/2021 - 10/2007
4	Breast Neoplasms (Breast Cancer) 01/2018 - 04/2013
4	Prostatic Neoplasms (Prostate Cancer) 01/2014 - 02/2007
3	Arthritis (Polyarthritis) 01/2022 - 01/2015
3	Parkinson Disease (Parkinson's Disease) 10/2021 - 05/2018
3	Cardiotoxicity 11/2020 - 01/2014
3	Rheumatoid Arthritis 10/2017 - 01/2015
3	Insulin Resistance 01/2015 - 01/2012
3	Liver Neoplasms (Liver Cancer) 08/2014 - 10/2012
3	Nasopharyngeal Carcinoma 10/2012 - 01/2012
3	Leukemia 06/2004 - 07/2002
2	Inflammation (Inflammations) 07/2022 - 01/2022
2	Reperfusion Injury 05/2022 - 01/2019
2	Mitochondrial Diseases (Mitochondrial Disease) 02/2021 - 12/2016
2	Autistic Disorder (Autism) 01/2021 - 07/2013
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2020 - 11/2018
2	Non-alcoholic Fatty Liver Disease 05/2019 - 01/2015
2	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 12/2016
2	Cognitive Dysfunction 01/2019 - 12/2016
2	Osteoporosis 06/2017 - 01/2017
2	Body Weight (Weight, Body) 01/2017 - 10/2012
2	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2016 - 07/2015
2	Poisoning 06/2016 - 12/2012
2	Human Influenza (Influenza) 11/2013 - 08/2009
2	Influenza in Birds (Avian Flu) 11/2013 - 08/2009
2	Colorectal Neoplasms (Colorectal Cancer) 10/2013 - 12/2011
2	B-Cell Leukemia (Leukemia, B Cell) 06/2004 - 07/2002
2	Lymphoma (Lymphomas) 06/2004 - 07/2002
1	Brain Ischemia (Cerebral Ischemia) 05/2022
1	Drug-Related Side Effects and Adverse Reactions 01/2022
1	Thrombocytopenia (Thrombopenia) 01/2022
1	Hypoxia (Hypoxemia) 09/2020
1	Fatty Liver 05/2019

Drug/Important Bio-Agent (IBA)

8	SaponinsIBA 05/2022 - 10/2012
7	TriterpenesIBA 10/2017 - 09/2004
6	Pharmaceutical PreparationsIBA 02/2021 - 04/2013
6	bufadienolideIBA 02/2021 - 06/2013
6	BufanolidesIBA 11/2020 - 10/2012
5	chan su (ChanSu)IBA 02/2021 - 10/2012
5	Adenosine Triphosphatases (ATPase)IBA 11/2020 - 01/2014
4	arenobufaginIBA 01/2018 - 06/2013
4	di wuIBA 10/2017 - 01/2015
3	Antineoplastic Agents (Antineoplastics)IBA 11/2020 - 06/2013
3	GlycosidesIBA 05/2019 - 06/2003
3	Biological ProductsIBA 01/2019 - 07/2012
3	Adenosine Triphosphate (ATP)IBA 01/2019 - 06/2014
3	Betulinic AcidIBA 12/2016 - 11/2002
3	AndrogensIBA 01/2014 - 02/2007
3	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2004 - 07/2002
2	Neuroprotective AgentsIBA 05/2022 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 05/2022 - 01/2019
2	Oxygen (Dioxygen)IBA 05/2022 - 01/2019
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021 - 07/2015
2	ProdrugsIBA 11/2020 - 01/2017
2	AlkaloidsIBA 01/2020 - 10/2013
2	LipidsIBA 05/2019 - 01/2015
2	Amphibian VenomsIBA 04/2019 - 06/2013
2	Capsules (Microcapsules)IBA 06/2017 - 01/2017
2	xian ling gu baoIBA 06/2017 - 01/2017
2	Collagen Type II (Type II Collagen)IBA 01/2017 - 01/2015
2	anhuienoside CIBA 01/2017 - 03/2015
2	AcidsIBA 05/2015 - 11/2010
2	Ethanol (Ethyl Alcohol)IBA 03/2014 - 06/2003
2	bufalinIBA 01/2014 - 10/2012
2	SteroidsIBA 10/2013 - 07/2012
2	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2012 - 06/2011
2	Antiviral Agents (Antivirals)IBA 08/2009 - 04/2003
2	23-hydroxybetulinic acidIBA 09/2004 - 11/2002
1	LipopolysaccharidesIBA 07/2022
1	serum P-component (CIt)IBA 01/2022
1	Interleukin-2 (IL2)IBA 01/2022
1	CarrageenanIBA 01/2022
1	proanthocyanidin A1IBA 01/2022
1	Interleukin-5 (Interleukin 5)IBA 01/2022
1	Interleukin-4 (Interleukin 4)IBA 01/2022
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 10/2021
1	Amino Acids FDA Link 10/2021
1	Caspase 3 (Caspase-3)IBA 02/2021
1	Caspase 9IBA 02/2021
1	PiperazineIBA 01/2021
1	Poly (ADP-Ribose) Polymerase-1IBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	celastrolIBA 01/2021
1	ApigeninIBA 01/2021
1	ErbB Receptors (EGF Receptor)IBA 10/2020
1	apigenin-6,8-di-C-glycopyranosideIBA 05/2019
1	FlavonoidsIBA 05/2019
1	isoschaftosideIBA 05/2019
1	schaftosideIBA 05/2019
1	Alanine Transaminase (SGPT)IBA 05/2019
1	schizandrin BIBA 01/2019
1	Glycogen Synthase (Synthase I)IBA 01/2019
1	EnzymesIBA 01/2019
1	catechol (pyrocatechol)IBA 01/2019

Therapy/Procedure

10	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022 - 03/2007
7	Drug Therapy (Chemotherapy) 01/2022 - 06/2013
7	Therapeutics 01/2021 - 08/2009
4	Oral Administration 01/2022 - 01/2017
1	Molecular Targeted Therapy 10/2020